buy Apixaban in uk
Buy Apixaban in uk
What is Apixaban?
Apixaban is an oral anticoagulant, part of a newer class of blood thinners known as direct oral anticoagulants (DOACs). Unlike traditional blood thinners like warfarin, which require regular monitoring and dietary restrictions, apixaban offers several advantages, including more predictable dosing and fewer interactions with food and other medications.
How Does Apixaban Work?
Apixaban works by inhibiting a protein in the blood called Factor Xa. Factor Xa plays a crucial role in the coagulation cascade, which is the process that helps blood to clot. By inhibiting Factor Xa, apixaban helps to prevent the formation of clots, reducing the risk of dangerous conditions such as:
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Stroke (especially in people with atrial fibrillation)
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Deep vein thrombosis (DVT)
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Pulmonary embolism (PE)
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Recurrence of DVT or PE
Since apixaban directly targets Factor Xa, it provides a precise mechanism of action that helps prevent blood clots from forming without requiring frequent blood tests to monitor its effects.
Key Uses of Apixaban ( Eliquis)
Apixaban is commonly prescribed for several clinical scenarios:
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Atrial Fibrillation (AFib): AFib is a common heart rhythm disorder that increases the risk of stroke due to the formation of blood clots in the heart. Apixaban is often prescribed to reduce this risk in patients with non-valvular AFib.
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Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE): These are conditions where blood clots form in the veins (DVT) or travel to the lungs (PE), which can be life-threatening. Apixaban is used both to treat and prevent these conditions.
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Prevention of DVT After Surgery: People who undergo certain surgeries, like hip or knee replacements, are at higher risk of developing blood clots. Apixaban is prescribed to reduce this risk in the post-operative period.
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Prevention of Stroke in Certain Patients with Atrial Fibrillation: Apixaban can significantly reduce the likelihood of a stroke in individuals with AFib who are at high risk.
Dosage and Administration
Apixaban is typically taken as a tablet, usually twice a day. The exact dosage depends on the condition being treated and the patient’s individual health factors. For most conditions, the recommended dose is 5 mg twice daily. However, for patients with certain risk factors like renal impairment or those who are elderly, a lower dose may be prescribed.
One of the key benefits of apixaban is that it does not require regular blood tests (such as the INR tests needed for warfarin). However, it is still important to adhere to the prescribed dosage and consult with a healthcare provider before making any changes to the regimen.
Side Effects of Apixaban
Like any medication, apixaban can cause side effects. However, not everyone will experience them, and many of the side effects are mild. Common side effects include:
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Bleeding: As a blood thinner, the most significant risk with apixaban is bleeding. This can range from minor bruising to more serious bleeding events, such as gastrointestinal bleeding or intracranial hemorrhage (bleeding in the brain).
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Anemia: Some people taking apixaban may develop anemia, which is a condition where the body does not have enough healthy red blood cells to carry oxygen.
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Nausea, fatigue, or dizziness: Some individuals may feel lightheaded, nauseous, or tired when using this medication.
In rare cases, apixaban may cause severe allergic reactions, such as difficulty breathing or swelling of the face and throat. If you experience any of these symptoms, it is essential to seek medical attention immediately.
Precautions and Considerations
While apixaban offers many benefits, there are some important precautions to keep in mind:
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Kidney and Liver Function: People with impaired kidney or liver function should use apixaban with caution. The medication may need to be adjusted, or an alternative anticoagulant may be considered.
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Bleeding Risk: Because apixaban increases the risk of bleeding, it should be used cautiously in patients with a history of bleeding disorders, ulcers, or recent surgery.
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Drug Interactions: Although apixaban has fewer drug interactions compared to warfarin, it can still interact with certain medications, including other anticoagulants, antifungals, and some HIV medications. Always inform your doctor of all medications you are taking.
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Pregnancy and Breastfeeding: Apixaban is generally not recommended during pregnancy, particularly in the first trimester, as it can pose a risk to the developing fetus. Women who are breastfeeding should also consult their healthcare provider before starting apixaban.
Reversal of Apixaban
In the case of an emergency, such as uncontrolled bleeding, it may be necessary to reverse the effects of apixaban. Fortunately, there is a specific reversal agent for apixaban called andexanet alfa (Andexxa), which can help to counteract its anticoagulant effects and stop bleeding.
Conclusion
Apixaban is an effective and widely used anticoagulant that helps prevent blood clots and reduce the risk of stroke, DVT, and PE. With its ease of use, fewer dietary restrictions, and less frequent need for monitoring compared to older blood thinners, it has become a preferred option for many patients. However, it is essential to follow the prescribed dosage carefully and be aware of the potential risks, especially concerning bleeding. Always consult with a healthcare professional before starting or stopping any medication to ensure the safest and most effective treatment plan for your health needs.
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