Zepbound

Description

How should I use Zepbound?

You should follow the directions on your prescription label carefully and ask your pharmacist or doctor to explain any part you do not understand. It is important to use this medicine exactly as directed. Do not take more or less of it or more often than your doctor prescribes.buy zepbound online

buy zepbound online is a pre-filled pen injected under the skin (subcutaneously).

Zepbound is usually given:

• once a week
• can be given with or without meals at any time of the day
• may be injected into the thigh, abdomen, or upper arm
• you should rotate the injection site with each dose

Your doctor will usually start you on a low dose, which will gradually increase, but not more than once every 4 weeks.

You may change the day of the week you use this medicine as long as there is at least three days between doses.

Zepbound Dosing Information

Usual Zepbound Adult Dose for Weight Loss

Initial dose: 2.5 mg under the skin (subcutaneously) once a week.

After 4 weeks: The dosage should be increased to 5 mg subcutaneously once a week.

Further dose increases: After at least 4 weeks on the current dose the dosage may be increased in 2.5 mg increments.

Recommended maintenance dose:  5 mg, 10 mg, or 15 mg injected subcutaneously once weekly.

Maximum dose: 15 mg subcutaneously once a week.

What should I do if I miss a dose?

Take the missed dose as soon as you remember it within 4 days after the missed dose. However, if more than 4 days have passed, skip the missed dose and continue your regular dosing schedule. Do not inject two doses within 3 days of each other.

Before using this medicine

You should not use Zepbound if you:

• are allergic to the tirzepatide or any ingredients contained in this medicine; see ingredients at the bottom of this page.
• have a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer); or
• multiple endocrine neoplasia type 2 (tumors in your glands).

Tell your doctor if you have ever had:

• pancreas problems;
• kidney disease;
• a severe stomach problem such as problems with digesting food or slowed emptying of your stomach (gastroparesis); or
• diabetic retinopathy (a diabetes complication that affects the eyes).

• How much weight is lost on Zepbound?

  Patients on Zepbound (tirzepatide) 5mg weekly lost 16.1 kg (35.5 lb) on average after 72 weeks. For Zepbound 10mg weekly dose, the average weight loss was 22.2 kg (48.9 lb), and for Zepbound 15mg weekly dose average weight loss was 23.6 kg (52.0 lb) over 72 weeks. Patients who used a placebo lost 2.4 kg (5.3 lb) over the 72 weeks. These results are from the clinical trial SURMOUNT-1, NCT04184622.  Individual results may vary.

• What are the side effects of Zepbound?

  Common Zepbound side effects

  The most common Zepbound side effects include abdominal pain, burping, constipation, diarrhea, dyspepsia, fatigue, gastroesophageal reflux disease, hair loss, hypersensitivity reactions, injection site reactions, nausea, and vomiting which affects 5% or more patients.

  Serious Zepbound side effects

  Stop using this medicine and get emergency medical help if you have:

  • signs of an allergic reaction: hives; difficulty breathing; feeling light-headed; swelling of your face, lips, tongue, or throat; or
  • pancreatitis with symptoms of severe pain in your upper stomach spreading to your back, nausea and vomiting.

  Call your doctor at once if you have:

  • severe stomach problems;
  • eye side effects or vision changes, including blurry vision or blurred vision;
  • signs of a thyroid tumor symptoms may include swelling or a lump in your neck, trouble swallowing, a hoarse voice, or if you feel short of breath;
  • gallbladder problem with symptoms including chalky-colored stools, stomach pain after eating, nausea, heartburn, bloating, and severe upper stomach pain that may spread to your back;
  • low blood sugar symptoms may include headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or
  • kidney problems with little or no urination, swelling in your feet or ankles, feeling tired or short of breath.

  This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.